The present study was conducted to investigate the effects of Nigella sativa and Lepidium sativum on the pharmacokinetics of cyclosporine in rabbits. Two groups of animals were treated separately with Nigella sativa (200 mg/kg p.o.) or Lepidium sativum (150 mg/kg p.o.) for eight consecutive days. On the 8th day, cyclosporine (30 mg/kg p.o.) was administered to each group one hour after herbal t...

An investigation was carried out to evaluate the insecticidal activity of Allium sativum, Zingiber officinale and Nigella sativa extracts against the larvae of T. granarium under laboratory conditions in the University of Agriculture, Faisalabad, Pakistan during 2009-10. The highest concentration of (6 %) Z. officinale was found to be comparatively more toxic (16.70 %) than those of A. sativum ...

abstract   introduction: diabetes mellitus accompanies with disturbances in learning, memory, and cognitive skills in the human society and experimental animals. considering the beneficial antidiabetic potential of nigella sativum (ns ), this research study was conducted to evaluate the effect of chronic consumption of ns on learning and memory in diabetic rats using passive avoidance and y-maz...

This survey was undertaken in the Errachidia province in south-eastern Morocco in order to inventory the main medicinal plants used in folk medicine to treat arterial hypertension and diabetes mellitus. Four hundred individuals who knew about and/or had used the medicinal plants for the indicated diseases, including some herbal healers, were interviewed throughout different regions of the provi...

abstract  introduction: diabetic rats display exaggerated hyperalgesic behavior in response to noxious stimuli that may resemble and model aspects of painful diabetic neuropathy in humans. this study was designed to investigate the effect of nigella sativum (ns) on formalin-induced nociceptive responses (standard formalin test) in streptozotocin (stz)-induced diabetic rats.  methods: for this p...

  Abstract  Introduction: Diabetic rats display exaggerated hyperalgesic behavior in response to noxious stimuli that may resemble and model aspects of painful diabetic neuropathy in humans. This study was designed to investigate the effect of Nigella sativum (NS) on formalin-induced nociceptive responses (standard formalin test) in streptozotocin (STZ)-induced diabetic rats.  Methods: For this...

introduction: some studies have demonstrated the potential of herbal drugs for the treatment of various diseases associated with impaired vascular nitric oxide (no). for diagnosis of the mechanism of these herbal plants, it seems necessary to evaluate the herbal extracts on the endothelium cell. the aim of the study was to investigate the effect of extract of trigonella foenum-graecum (t.foenum...

Infection with Helicobacter pyloriis the most common cause of stomach and duodenal ulcers. About more than 80 % of people are infected with H. pylori in developing countries. H. pylori uses urease enzyme product "ammonia" in order to neutralize and protect itself from the stomach acidic condition and urease enzyme activity has been shown to be essential to the colonization of H. pylori. Inhibit...

Spices have been widely used as food flavorings and folk medicines for thousands of years. Numerous studies have documented the antioxidant, anti-inflammatory and immunomodulatory effects of spices, which might be related to prevention and treatment of several cancers, including lung, liver, breast, stomach, colorectum, cervix, and prostate cancers. Several spices are potential sources for prev...